Klinisk og eksperimentell kardiovaskulær overvåkning
Gruppen har som mål å utvikle og teste ny teknologi for, kardiovaskulær overvåkning, kardiovaskulær respons på nye kardiovaskulære terapier og
myokardfunksjon i terapeutisk hypotermi og alvorlig sepsis.
Kontaktinformasjon
Gruppeleder Per Steinar Halvorsen.
Telefon: 23 07 01 00
Mobil: 46 43 14 99
E-post: sthalvor@ous-hf.no
Kontaktinformasjon til gruppens medlemmer finnes lengre ned på siden.
Besøksadresse og postadresse
The Intervention Centre, Division of Emergencies and Critical Care, Rikshospitalet, Postboks 4950, 0424 Oslo
Beskrivelse av forskningsprofil
Main aims:
Develop and test new technologies in cardiovascular monitoring
Cardiovascular response to new cardiovascular therapies
Myocardial function in therapeutic hypothermia and severe sepsis
This includes evaluating hemodynamic responses of
new cardiovascular image guided procedures
ECMO strategies
treatment for end stage heart failure with ventricular assist devices (VAD)
Langsiktig mål
To translate new concepts in technology and physiology into clinical practice.
Hovedmedlemmer
Seniorforskere:
Jan Fredrik Bugge, Department of Anesthesiology.jbugge@ous-hf.no
Mohammad Albatat, MSc, The Intervention Centre,
malbatat.90@gmail.com. PACEMAKER/CRT
TAVI: is myocardial reserve related to long term outcome?
Accelerometer for detection of thromboembolic events in LVAD
Accelerometer/gyro/magnetometer for monitoring changes in right and left ventricular load and detection of graded myocardial ischemia.
Can betablockers improve survival and cardiovascular function after cardiac arrest: an experimental ECMO study
Left and right ventricular dysfunction in severe sepsis; the effect of pulmonary hypertension and interventricular septal shift
Myocardial effects of therapeutic hypothermia in cardiac surgery
Effects of epinephrine and betablockers on systolic and diastolic left ventricular function during therapeutic hypothermia
Multifunctional pacemaker systems for cardiac resynchronization therapy (CRT)
OSCAR research network at Oslo University Hospital: Professor K. Sunde
WiBEC EU-project at The Intervention Centre: Professor Ilangko Balasingham,
Biosensor Research Group at Oslo University Hospital: Professor T. I. Tønnessen
Complement Research Group at Oslo University Hospital: Professor Tom Eirik Mollnes
University College of Southeast Norway: Professor Kristin Imenes
Hyler S, Espinoza A, Skulstad H, Fosse E,
Halvorsen PS.Left ventricular function can be continuously monitored with an epicardially attached accelerometer sensor.Eur J Cardiothorac Surg. 2014;(2): PMID:24482390
Grymyr OH, Nguyen AT, Tjulkins F, Espinoza A, Remme EW, Skulstad H, Fosse E, Imenes K,
Halvorsen PS.
Continuous monitoring of cardiac function by 3-dimensional accelerometers in a closed-chest pig model.Interact Cardiovasc Thorac Surg. 2015; 21:573-82. doi: 10.1093/icvts/ivv191. PMID: 26254463
Grymyr OJ, Beitnes JO, Eidet J,Tølløfsrud S, Fiane F, Skulstad H, Fosse E,
Halvorsen PS.Detection of intraoperative myocardial dysfunction by accelerometer during aortic valve replacement.Interact CardioVasc Thorac Surg 2016; doi:10.1093/icvts/ivw326.
Krogh MR, Nghiem GM,
Halvorsen PS, Elle OJ, Grymyr OJ, Hoff L, Remme EW.Gravity Compensation Method for Combined Accelerometer and Gyro Sensors Used in Cardiac Motion Measurements. Ann Biomed Eng. 2017. doi: 10.1007/s10439-017-1798-4. PMID: 28116541
Espinoza A, Halvorsen PS, Skulstad H, Lundblad R, Bugge JF, Hoff L, Fosse E, Edvardsen T. Automated detection of myocardial ischaemia by epicardial miniature ultrasound transducers-a novel tool for patient monitoring during cardiac surgery.Eur J Cardiothorac Surg. 2011 PMID:20627751
Hyler S, Pischke SE, Halvorsen PS, Espinoza A, Bergsland J, Tønnessen TI, Fosse E, Skulstad H. Continuous monitoring of regional function by a miniaturized ultrasound transducer allows early quantification of low-grade myocardial ischemia.J Am Soc Echocardiogr. 2015;28:486-94. PMID:25636368
Eidet J, Dahle G, Bugge JF, Bendz B, Rein KA, Aaberge L, Offstad JT, Fosse E, Aakhus S,
Halvorsen PS.Long-term outcomes after transcatheter aortic valve implantation: the impact of intraoperative tissue Doppler echocardiography. Interact Cardiovasc Thorac Surg. 2016;23(3):403-9. doi: 10.1093/icvts/ivw159. PMID: 27241050
Bergan HA,
Halvorsen PS, Skulstad H, Fosse E, Bugge JF.Does therapeutic hypothermia during extracorporeal cardiopulmonary resuscitation preserve cardiac function?J Transl Med. 2016 Dec 20;14:345. doi: 10.1186/s12967-016-1099-y
Espinoza A, Kerans V, Opdahl A, Skulstad H, Halvorsen PS, Bugge JF, Fosse E, Edvardsen T. Effects of therapeutic hypothermia on left ventricular function assessed by ultrasound imaging.J Am Soc Echocardiogr. 2013;26(11). PMID:23891124
Hestenes SM, Halvorsen PS, Skulstad H, Remme EW, Espinoza A, Hyler S, Bugge JF, Fosse E, Nielsen EW, Edvardsen T. Myocardial function in therapeutic hypothermia and severe sepsis. Advantages of strain echocardiography in assessment of myocardial function in severe sepsis: an experimental study. Crit Care Med. 2014: PMID:24633187