NOSVAR Publikasjoner i 2025

Publikasjoner i 2025 med bruk av materiale fra NOSVAR og RHI-biobank

Totalt 19 publikasjoner med data fra register og RHI-biobank er publisert i 2025. Studiene er gjort på følgende diagnoser; Systemisk sklerose (10), SLE (3), Sjøgren (2), Myositt (1) og Vaskulitt (3). Forfattere fra Seksjon for revmatologi, OUS Rikshospitalet er markert med fet skrift.

Systemisk sklerose og fibroserende lungesykdommer

A comparative analysis of risk stratification tools in SSc-associated pulmonary arterial hypertension: a EUSTAR analysis. Bjørkekjær HJ, Bruni C, Broch K, Brunborg C, Carreira PE, Airò P, Simeón-Aznar CP, Truchetet ME, Giollo A, Balbir-Gurman A, Martin M, Denton CP, Gabrielli A, Del Galdo F, Vonk MC, Fretheim H, Bitter H, Midtvedt Ø, Andreassen A, Høie S, Tanaka Y, Riemekasten G, Müller-Ladner U, Matucci-Cerinic M, Castellví I, Siegert E, Hachulla E, Molberg Ø, Distler O, Hoffmann-Vold AM; EUSTAR Collaborators. Rheumatology (Oxford). 2025 Jun 1;64(6):3643-3656. doi: 10.1093/rheumatology/keaf053.

A screening tool to detect interstitial lung disease in systemic sclerosis: the ILD-RISC score. Cosimo Bruni, Lorenzo Tofani, Håvard Fretheim, Sophie I E Liem, Arthiha Velauthapillai, Hilde Bjørkekjær, Imon Barua, Ilaria Galetti, Alexandru Garaiman, Mike O Becker, Anna-Maria Hoffmann-Vold, Jeska de Vries-Bouwstra, Madelon C Vonk, Jörg H W Distler, Marco Matucci-Cerinic, Oliver Distler. Rheumatology, Volume 64, Issue 12, December 2025, Pages 6285–6293. doi: 10.1093/rheumatology/keaf445

Deep hierarchical subtyping of multi-organ systemic sclerosis trajectories - a EUSTAR study. Trottet, C., Schürch, M., Hoffmann-Vold AM, et al. npj Digit. Med. 8, 563 (2025). doi: 10.1038/s41746-025-01962-y

Evaluation of Systemic Sclerosis Primary Heart Involvement and Chronic Heart Failure in the European Scleroderma Trials and Research Cohort. Györfi AH, Filla T, Polzin A, Tascilar K, Buch M, Tröbs M, Matei AE, Airo P, Balbir-Gurman A, Kuwert F, Mihai C, Kabala A, Graßhoff H, Callaghan J, Isomura Y, Mansour J, Spierings J, Tennoe AH, Selvi E, Riccieri V, Hoffmann-Vold AM, Bergmann C, Schett G, Hunzelmann N, van Laar JM, Saketkoo LA, Kuwana M, Siegert E, Riemekasten G, Distler O, du Four T, Smith V, Truchetet ME, Distler JHW; EUSTAR collaborators. J Am Heart Assoc. 2025 Mar 4;14(5):e036730. doi: 10.1161/JAHA.124.036730. Epub 2025 Feb 26.

Faecal microbiota transplantation in patients with systemic sclerosis and lower gastrointestinal tract symptoms in Norway (ReSScue): a phase 2, randomised, double-blind, placebo-controlled trial. Fretheim H, Barua I, Bakland G, Dhainaut A, Halse AK, Carstens MN, Didriksen H, Midtvedt Ø, Lundin KEA, Aabakken L, Sarna VK, Zaré HK, Khanna D, Distler O, Midtvedt T, Bækkevold ES, Olsen IC, Domanska D, Pesonen ME, Molberg Ø, Hoffmann-Vold AM. Lancet Rheumatol. 2025 May;7(5):e323-e332. doi: 10.1016/S2665-9913(24)00334-5. Epub 2025 Jan 31. PMID: 39900089.

Gastroesophageal reflux disease is associated with a more severe interstitial lung disease in systemic sclerosis in the EUSTAR cohort. Eliane Roth, Cosimo Bruni, Liubov Petelytska, Mike Oliver Becker, Rucsandra Dobrota, Suzana Jordan, Carina Mihai, Sinziana Muraru, Patricia E Carreira, Jeska De Vries-Bouwstra, Yolanda Braun-Moscovici, Vasiliki Liakouli, Gianluca Moroncini, Christina Bergmann, Luc Mouthon, Christopher P Denton, Maria De Santis, Alberto Cauli, Sabine Adler, Vera Bernardino, Marie-Elise Truchetet, Madelon Vonk, Francesco Del Galdo, Anna-Maria Hoffmann-Vold, Oliver Distler, Muriel Elhai, EUSTAR Collaborators. Rheumatology, Volume 64, Issue SI, December 2025, Pages SI63–SI72. doi: 10.1093/rheumatology/keaf016

Lung function and skin fibrosis changes as predictors of survival in SSc-associated interstitial lung disease: a EUSTAR study. Vincent Sobanski, Jeska de Vries-Bouwstra, Anna-Maria Hoffmann-Vold, Dörte Huscher, Margarida Alves, Marco Matucci-Cerinic, Gabriela Riemekasten, Mengtao Li, László Czirják, Otylia Kowal-Bielecka, Yannick Allanore, Nils Schoof, Oliver Distler, EUSTAR Collaborators. Rheumatology, Volume 64, Issue 10, October 2025, Pages 5344–5353, doi: 10.1093/rheumatology/keaf264

Post hoc comparison of the effectiveness of tocilizumab, rituximab, mycophenolate mofetil, and cyclophosphamide in patients with SSc-ILD from the EUSTAR database. Qingran Yan, Cosimo Bruni, Alexandru Garaiman, Carina Mihai, Suzana Jordan, Mike Oliver Becker, Muriel Elhai, Rucsandra Dobrota, Petelytska Liubov, Joerg Henes, Eric Hachulla, Elise Siegert, Alexandra Balbir-Gurman, Giovanna Cuomo, Gabriela Riemekasten, Stefan Heitmann, Davide Mohammad Reza Beigi, Susanne Ullman, Petros Sfikakis, Francesca Ingegnoli, Vera Bernardino, Marie-Elise Truchetet, Madelon Vonk, Francesco Del Galdo, Anna-Maria Hoffmann-Vold, Ye Shuang, Oliver Distler. Annals of the Rheumatic Diseases, Volume 84, Issue 4, 2025, Pages 620-631. doi: 10.1016/j.ard.2025.01.014.

Predicting the risk of subsequent progression in patients with systemic sclerosis-associated interstitial lung disease with progression: a multicentre observational cohort study. Anna-Maria Hoffmann-Vold, Liubov Petelytska, Håvard Fretheim, Trond Mogens Aaløkken, Mike Oliver Becker, Hilde Jenssen Bjørkekjær, Cathrine Brunborg, Cosimo Bruni, Christian Clarenbach, Phuong Phuong Diep, Rucsandra Dobrota, Michael T Durheim, Muriel Elhai, Thomas Frauenfelder, Suiyuan Huang, Suzana Jordan, Emily Langballe, Øyvind Midtvedt, Carina Mihai, Erica Mulcaire-Jones, Janelle Vu Pugashetti, Marco Sprecher, Justin Oldham, Øyvind Molberg, Dinesh Khanna, Oliver Distler. The Lancet Rheumatology, Volume 7, Issue 7, 2025, Pages e463-e471. doi: 10.1016/S2665-9913(25)00026-8.

Validation of a semi-quantitative method to assess interstitial lung disease severity and progression in systemic sclerosis by standard and low-dose HRCT scans. Lucas Tschalèr, Suzana Jordan, Trond Mogens Aaløkken, Mike Becker, Cathrine Brunborg, Cosimo Bruni, Christian Clarenbach, Rucsandra Dobrota, Michael Thomas Durheim, Muriel Elhai, Thomas Frauenfelder, Håvard Fretheim, Torhild Garen, Øyvind Midtvedt, Carina Mihai, Øyvind Molberg, Oliver Distler, Anna-Maria Hoffmann-Vold. RMD Open. 2025;11:e004938. https://doi.org/10.1136/rmdopen-2024-004938

Systemisk lupus erythematosus (SLE)

Accrual of thromboembolic events and antiphospholipid syndrome in new-onset systemic lupus erythematosus: a population-based inception cohort study. Moe SR, Haukeland H, Brunborg C, Botea A, Damjanic N, Wivestad GÅ, Øvreås HK, Bøe TB, Orre A, Torhild G, Provan SA, Molberg Ø, Lerang K. RMD Open. 2025 Sep 2;11(3):e005795. doi: 10.1136/rmdopen-2025-005795.

Cardiovascular risk factor control in antiphospholipid syndrome, and differences between primary and systemic lupus erythematosus-related antiphospholipid syndrome (SURF-SLE and APS project): a cross-sectional study of 1003 individuals from 11 countries. Eleana Bolla, Anne Grete Semb, Prof Michelle Petri, Prof Petros P Sfikakis, Bahar Artim-Esen, Gabriela Hernandez-Molina, Prof Eric Hachulla, Prof Haner Direskeneli, Prof George A Karpouzas, Dina Zucchi, Mohit Goyal, Prof Nathalie Costedoat-Chalumeau, Prof Angela Tincani, Ayten Yazici, Karoline Lerang, Anne Troldborg, Sofia Ajeganova, Tatiana V Popkova, Elisabet Svenungsson, Nikos Pantazis, Prof Maria G Tektonidou, on behalf of the SURF-SLE and APS collaborators The Lancet Rheumatology, Volume 8, Issue 3, e192 - e203.

Genetic risk factors and clinical manifestations of systemic lupus erythematosus: Large-scale analysis of genetic predisposition and disease subtypes. Reid S, Sandling JK, Pucholt P, Sayadi A, Frodlund M, Lerang K, Gunnarsson I, Jönsen A, Syvänen AC, Molberg Ø, Rantapää-Dahlqvist S, Rudin A, Sjöwall C, Svenungsson E, Bengtsson AA, Rönnblom L, Leonard D. J Intern Med. 2026 Jan;299(1):95-108. doi: 10.1111/joim.70040. Epub 2025 Nov 7.

Sjøgren

abs0838 improving early ild detection in sjögren disease: a risk estimation tool for clinical practice. A.M. Hoffmann-Vold, K. Kastrati, M. Sprecher, E. Langballe, P.P. Diep, H. Fretheim, H. Andersson, P. Studenic, B. Müller-Durovic, C. Brunborg, D.C. Bruni, C. Clarenbach, T. Frauenfelder, T.M. Aaløkken, N. Moe, H. Prosch, Ø. Molberg, O. Distler. Annals of the Rheumatic Diseases, Volume 84, 2094 - 2095.

Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland. Wiley MM, Radziszewski M, Khatri B, Joachims ML, Tessneer KL, Stolarczyk AM, Yao S, Li J, Pritchett-Frazee C, Johnston AA, Rasmussen A, Anaya JM, Aqrawi LA, Bae SC, Baecklund E, Björk A, Brun JG, Bucher SM, Dand N, Eloranta ML, Engelke F, Forsblad-d'Elia H, Fugmann C, Glenn SB, Gong C, Gottenberg JE, Hammenfors D, Imgenberg-Kreuz J, Jensen JL, Johnsen SJA, Jonsson MV, Kelly JA, Khanam S, Kim K, Kvarnström M, Mandl T, Martín J, Morris DL, Nocturne G, Norheim KB, Olsson P, Palm Ø, Pers JO, Rhodus NL, Sjöwall C, Skarstein K, Taylor KE, Tombleson P, Thorlacius GE, Venuturupalli SR, Vital EM, Wallace DJ, Radfar L, Brennan MT, James JA, Scofield RH, Gaffney PM, Criswell LA, Jonsson R, Appel S, Eriksson P, Bowman SJ, Omdal R, Rönnblom L, Warner BM, Rischmueller M, Witte T, Farris AD, Mariette X, Shiboski CH; Sjögren’s International Collaborative Clinical Alliance (SICCA); Wahren-Herlenius M, Alarcón-Riquelme ME; PRECISESADS Clinical Consortium; Ng WF; UK Primary Sjögren’s Syndrome Registry; Sivils KL, Guthridge JM, Adrianto I, Vyse TJ, Tsao BP, Nordmark G, Lessard CJ. Ann Rheum Dis. 2025 Sep;84(9):1512-1527. doi: 10.1016/j.ard.2025.04.023. Epub 2025 May 30.

Myositt

Shared genetic susceptibility between idiopathic inflammatory myopathies and common B cell lymphoma subtypes found primarily in the human leucocyte antigen region. Che WI, Öberg Sysojev A, Zhu C, Patasova K, Smedby KE, Lundberg IE, Molberg, Ø et al. RMD Open. 2025;11:e006035. doi: 10.1136/rmdopen-2025-006035

Vaskulitt

Incidence and prevalence of ANCA-associated vasculitis in Oslo, Norway, applying different criteria-based case definitions: a population-based cohort study. Kilian KR, Brunborg C, Holme SS, Torhild G, Gunnarsson R, Molberg Ø. RMD Open. 2025;11:e005526. doi: 10.1136/rmdopen-2025-005526

Incidence and prevalence of Behçet's disease in Oslo, Norway: a two-decade population-based analysis. Lorentsen JLL, Brunborg C, Aasebø AT, Valeur J, Haavardsholm EA, Molberg Ø, Palm Ø, Lerang K. Rheumatology (Oxford). 2025 Aug 1;64(8):4703-4712. doi: 10.1093/rheumatology/keaf224.

In-Depth Analysis of Disease Manifestations in Antineutrophil Cytoplasmic Antibody-Associated Vasculitides Identifies Distinct Clinical Phenotypes. Lindberg H, Knight A, Hellbacher E, Norling O, Berglin E, Stegmayr B, Baslund B, Palm Ø, Haukeland H, Gunnarsson I, Bruchfeld A, Weiner M, Eriksson P, Segelmark M, Ohlsson S, Mohammad AJ, Svärd A, Pullerits R, Herlitz H, Söderbergh A, Rantapää-Dahlqvist S, Dahlqvist J. ACR Open Rheumatol. 2025 Mar;7(3):e70009. doi: 10.1002/acr2.70009.

Abstractpresentasjoner

EULAR (European Congress of Rheumatology): 5
ACR (American Congress of Rheumatology): 1
ESR (European Congress of Radiology):1

Disputaser

Ingen disputaser i 2025