Prognostic value and outcome of left atrial and ventricular function and volume in acute myocardial infarction
This study investigates the prognostic role of left atrial (LA) function, including LA volume and LA strain, in patients with acute myocardial infarction (AMI). The goal is to assess whether LA strain adds further prognostic value to conventional markers such as LV global longitudinal strain (GLS) and indexed LA volume (LAVi) in predicting outcomes in AMI patients, including mortality and major adverse cardiovascular events (MACE).
This study, led by MD Jorun Tangen, evaluates the prognostic value of left atrial (LA) function, particularly LA volume and LA strain, in patients with acute myocardial infarction (AMI). The results suggest that LA strain, in addition to LA volume and left ventricular (LV) global longitudinal strain (GLS), is independently associated with all-cause mortality and major adverse cardiovascular events (MACE). LA reservoir strain is of particular importance in AMI patients with atrial fibrillation (AF), highlighting its potential for improving risk stratification in this patient population.

Related publications
- Reduced Cardiac Function by Echocardiography in a Minority of COVID-19 Patients 3 Months after Hospitalization (Link to publication)
- The Prognostic Value of Left Atrial Function in Patients with Acute Myocardial Infarction (Link to publicaton).
- Left atrial volume assessed by echocardiography identifies patients with high risk of adverse outcome after acute myocardial infarction (Link to publication).
Contributions
- Cardiac Function is Normal in Most Patients Recovered from COVID-19 (Link to publication)
- Hjertet fungerer normal hos de fleste som har hatt covid-19 (Link to forskning.no, in norwegian).
Researchers involved
- Jorun Tangen, MD/PhD-fellow, OUS
- Main supervisor: Thor Edvardsen, MD/Professor, OUS/UiO
- Co-supervisor: Kristina Haugaa, MD/Professor, OUS/UiO
- Co-supervisor: Helge Skulstad, MD/PhD, Ahus
Collaborators
- Lovisenberg Diakonale Hospital, Sørlandet Hospital Kristiansand