Publikasjoner i 2024

NOSVAR-registeret og biobanken danner kjernen for mye av forskningen som utføres ved seksjon for revmatologi og nytteverdien reflekteres i antall publikasjoner. Gjennom årenes løp har dette ledet til mange publikasjoner og doktorgrader.

Publikasjoner i 2024 med bruk av materiale fra NOSVAR og RHI-biobank

Totalt 18 publikasjoner med data fra register og RHI-biobank er publisert i 2024. Studiene er gjort på følgende diagnoser; Systemisk sklerose (6), SLE (2), Sjøgren (1), Myositter (7), Sjøgren/SLE/Myositt (1), vaskulitter (2).

Systemisk sklerose og fibroserende lungesykdommer

A validation of register-derived diagnoses of interstitial lung disease in patients with inflammatory arthritis: data from the NOR-DMARD study. Provan SA, Ahlfors F, Bakland G, Hu Y, Kristianslund EK, Ikdahl E, Kvien TK, Aaløkken TM, Hoffmann-Vold AM. Scand J Rheumatol. 2024 May;53(3):173-179. doi: 10.1080/03009742.2024.2306716.

Arthritis in patients with very early systemic sclerosis: a comprehensive clinical and prognostic analysis. Muraru S, Mihai C, Elhai M, Becker M, Jordan S, Garaiman A, Bruni C, Petelytska L, Hoffmann-Vold AM, Distler O, Dobrota R. Rheumatology (Oxford). 2024 May 9:keae247. doi: 10.1093/rheumatology/keae247.

Characteristics and disease course of untreated patients with interstitial lung disease associated with systemic sclerosis in a real-life two-centre cohort. Scheidegger M, Boubaya M, Garaiman A, Barua I, Becker M, Bjørkekjær HJ, Bruni C, Dobrota R, Fretheim H, Jordan S, Midtvedt O, Mihai C, Hoffmann-Vold AM, Distler O, Elhai M. RMD Open 2024;10:e003658. doi: 10.1136/rmdopen-2023-003658.

Clinical significance of the anti-Nucleolar Organizer Region 90 antibodies (NOR90) in systemic sclerosis: Analysis of the European Scleroderma Trials and Research (EUSTAR) cohort and a systematic literature review. Dima A, Vonk MC, Garaiman A, Kersten BE, Becvar R, Tomcik M, Hoffmann-Vold AM, Castellvi I, Jaime JT, Brzosko M, Milchert M, Krasowska D, Michalska-Jakubus M, Airo P, Matucci-Cerinic M, Bruni C, Iudici M, Distler J, Gheorghiu AM, Poormoghim H, Motta F, De Santis M, Parvu M, Distler O, Mihai C. Eur J Intern Med. 2024;125:104-110. doi: 10.1016/j.ejim.2024.03.035.

Histogram-Based Densitometry Index to Assess the Severity of Interstitial Lung Disease in Systemic Sclerosis in Standard and Low-Dose Computed Tomography. Bruni C, Tofani L, Garaiman A, Jordan S, Mihai CM, Dobrota R, Elhai M, Becker MO, Hoffmann-Vold AM, Frauenfelder T, Matucci-Cerinic M, Distler O. Journal of Rheumatology Feb 2024, jrheum.2023-0415; doi: 10.3899/jrheum.2023-0415.

The Performance of Pulmonary Function Tests in Predicting Systemic Sclerosis-Interstitial Lung Disease in the European Scleroderma Trial and Research Database. Lepri G, Bruni C, Tofani L, Moggi-Pignone A, Orlandi M, Tomassetti S, Hughes M, Del Galdo F, Irace R, Distler O, Riccieri V, Allanore Y, Gheorghiu AM, Siegert E, De Vries-Bouwstra J, Hachulla E, Tikly M, Damjanov N, Spertini F, Mouthon L, Hoffmann-Vold AM, Gabrielli A, Guiducci S, Matucci-Cerinic M, Furst D, Bellando-Randone S, Eustar Collaborators. Diagnostics 2024, 14(3), 295. doi: 10.3390/diagnostics14030295.

Systemisk lupus erythematosus (SLE)

Prevalence and target attainment of traditional cardiovascular risk factors in patients with systemic lupus erythematosus: a cross-sectional study including 3401 individuals from 24 countries. Bolla E, Semb AG, Kerola AM, Ikdahl E, Petri M, Pons-Estel GJ, Karpouzas GA, Sfikakis PP, Quintana R, Misra DP, Borba EF, Garcia-de la Torre I, Popkova TV, Artim-Esen B, Troldborg A, Fragoso-Loyo H, Ajeganova S, Yazici A, Aroca-Martinez G, Direskeneli H, Ugarte-Gil MF, Mosca M, Goyal M, Svenungsson E, Macieira C, Lerang K et al. The Lancet Rheumatology,
2024, Volume 6, Issue 7, e447 - e459. doi: 10.1016/S2665-9913(24)00090-0

Sensitivity of classification criteria from time of diagnosis in an in¬cident systemic lupus erythematosus cohort: a population-based study from Norway. Haukeland H, Moe SR, Brunborg C, Botea A, Damjanic N, Wivestad GÅ, Øvreås HK, Bøe TB, Orre A, Garen T, Sanner H, Lerang K, Molberg Ø. RMD Open 2024;10:e004395. doi: 10.1136/rmdopen-2024-004395

Sjøgren

A high polygenic risk score is associated with SSA/SSB antibody positivity and early onset in primary Sjögren's disease. Fugmann C, Reid S, Pucholt P, Kvarnström M, Björk A, Mofors J, Sjöwall C, Eriksson P, Olsson P, Mandl T, Forsblad-d'Elia H, Magnusson Bucher S, Johnsen SJ, Norheim KB, Appel S, Hammenfors D, Jensen JL, Palm Ø, Omdal R, Jonsson R, Baecklund E, Wahren-Herlenius M, Leonard D, Imgenberg-Kreuz J, Nordmark G. Rheumatology 2024 Dec 18:keae693. doi: 10.1093/rheumatology/keae693.

SLE, Sjøgren og Myositt

Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases. Bianchi, M., Kozyrev, S.V., Notarnicola, A., Sandling, J.K., Pettersson, M., Leonard, D., Sjöwall, C., Gunnarsson, I., Rantapää-Dahlqvist, S., Bengtsson, A.A., Jönsen, A., Svenungsson, E., Enocsson, H., Kvarnström, M., Forsblad-d'Elia, H., Bucher, S.M., Norheim, K.B., Baecklund, E., Jonsson, R., Hammenfors, D., Eriksson, P., Mandl, T., Omdal, R., Padyukov, L., Andersson, H., Molberg, Ø., Diederichsen, L.P., Syvänen, A.-C., Wahren-Herlenius, M., Nordmark, G., Lundberg, I.E., Rönnblom, L., Lindblad-Toh, K. Arthritis Rheumatol 2025, 77: 212-225. Epub ahead of print Sep 2024. doi: 10.1002/art.42988.

Myositt

Autoantibodies and damage in patients with idiopathic inflammatory myopathies: A longitudinal multicenter study from the MYONET international network. Espinosa-Ortega F, Lodin K, Dastmalchi M, Vencovsky J, Diederichsen LP, Shinjo SK, Danieli MG, Selva-O'Callaghan A, de Visser M, Griger Z, Ceribelli A, Gómez-Martin D, Andersson H, Vázquez-Del Mercado M, Chinoy H, Lilleker JB, New P, Krogh NS, Lundberg IE, Alexanderson H; MYONET Registry Study Group.Semin Arthritis Rheum. 2024 Oct;68:152529. doi: 10.1016/j.semarthrit.2024.152529.

Comparison of clinical features between patients with anti-synthetase syndrome and dermatomyositis: results from the MYONET registry. Hum RM, Lilleker JB, Lamb JA, Oldroyd AGS, Wang G, Wedderburn LR, Diederichsen LP, Schmidt J, Danieli MG, Oakley P, Griger Z, Nguyen Thi Phuong T, Kodishala C, Vazquez-Del Mercado M, Andersson H, De Paepe B, De Bleecker JL, Maurer B, McCann L, Pipitone N, McHugh N, New RP, Ollier WE, Krogh NS, Vencovsky J et al. Rheumatology 2024, 63(8), 2093-2100. doi: 10.1093/rheumatology/kead481.

Discovery of new myositis genetic associations through leveraging other immune-mediated diseases. Reales G, Amos CI, Benveniste O, Chinoy H, De Bleecker J, De Paepe B, Doria A, Gregersen PK, Lamb JA, Limaye V, Lundberg IE, Machado PM, Maurer B, Miller FW, Molberg Ø, Pachman LM, Padyukov L, Radstake TR, Reed AM, Rider LG, Rothwell S, Selva-O'Callaghan A, Vencovský J, Wedderburn LR; Myositis Genetics Consortium; Wallace C. HGG Adv. 2024 Oct 10;5(4):100336. doi: 10.1016/j.xhgg.2024.100336. Epub 2024 Jul 22.

Effect modification of cancer on the association between dysphagia and mortality in early idiopathic inflammatory myopathies. Leclair V, Notarnicola A, Kryštůfková O, Mann H, Andersson H, Diederichsen LP, Vencovský J, Holmqvist M, Lundberg IE, Steele RJ, Hudson M. Semin Arthritis Rheum. 2024;65:152408. doi: 10.1016/j.semarthrit.2024.152408.

Genetic Architecture of Idiopathic Inflammatory Myopathies From Meta-Analyses. Zhu, C., Han, Y., Byun, J., Xiao, X., Rothwell, S., Miller, F.W., Lundberg, I.E., Gregersen, P.K., Vencovsky, J., Shaw, V.R., McHugh, N., Limaye, V., Selva-O'Callaghan, A., Hanna, M.G., Machado, P.M., Pachman, L.M., Reed, A.M., Rider, L.G., Molberg, Ø., Benveniste, O., Radstake, T., Doria, A., De Bleecker, J.L., De Paepe, B., Maurer, B., Ollier, W.E., Padyukov, L., Wedderburn, L.R., Chinoy, H., Lamb, J.A., Amos, C.I. Arthritis Rheumatol 2025. Epub ahead of print Dec 2024.doi: 10.1002/art.43088

Patient global assessment and inflammatory markers in patients with idiopathic inflammatory myopathies - A longitudinal study. Lodin K, Espinosa-Ortega F, Dastmalchi M, Vencovsky J, Andersson H, Chinoy H, Lilleker JB, Shinjo SK, Maurer B, Griger Z, Ceribelli A, Torres-Ruiz J, Mercado M VD, Leonard D, Alexanderson H, Lundberg IE; MyoNet Registry Study Group. Semin Arthritis Rheum. 2024 Apr;65:152379. doi: 10.1016/j.semarthrit.2024.152379.

Vaskulitt

Risk loci involved in giant cell arteritis susceptibility: a genome-wide association study. Borrego-Yaniz G, Ortiz-Fernández L, Madrid-Paredes A, Kerick M, Hernández-Rodríguez J, Mackie SL, Vaglio A, Castañeda S, Solans R, Mestre-Torres J, Khalidi N, Langford CA, Ytterberg S, Beretta L, Govoni M, Emmi G, Cimmino MA, Witte T, Neumann T, Holle J, Schönau V, Pugnet G, Papo T, Haroche J, Mahr A, Mouthon L, Molberg Ø, Diamantopoulos AP, Voskuyl A, Daikeler T, Berger CT, Molloy ES, Blockmans D, van Sleen Y, Iles M, Sorensen L, Luqmani R, Reynolds G, Bukhari M, Bhagat S, Ortego-Centeno N, Brouwer E, Lamprecht P, Klapa S, Salvarani C, Merkel PA, Cid MC, González-Gay MA, Morgan AW, Martin J, Márquez A; Spanish GCA Group; UK GCA Consortium; Vasculitis Clinical Research Consortium. Lancet Rheumatol. 2024 Jun;6(6):e374-e383. doi: 10.1016/S2665-9913(24)00064-X.

The HLA region in ANCA-associated vasculitis: characterisation of genetic associations in a Scandinavian patient population. Lundtoft C, Knight A, Meadows JRS, Karlsson Å, Rantapää-Dahlqvist S, Berglin E, Palm Ø, Haukeland H, Gunnarsson I, Bruchfeld A, Segelmark M, Ohlsson S, Mohammad AJ, Eriksson P, Söderkvist P, Ronnblom L, Omdal R, Jonsson R, Lindblad-Toh K, Dahlqvist J. RMD Open. 2024;10(2):e004039. doi: 10.1136/rmdopen-2023-004039.